In a qualitative study, people with psoriasis described a unique set of social challenges related to their disease. Paras Karmacharya, MD, discusses why skin “remembers” irritation after Halloween and how to prevent future flares. Steven Feldman, MD, PhD, discusses whether physicians can balance professionalism and fun by wearing costumes on Halloween. Combination therapies for acne scarring consistently outperformed monotherapies in a network meta-analysis. Depression impacts anywhere from 9% to 55% of patients with psoriasis, depending on the study. How can dermatologists help? A surveillance program was associated with higher rates of skin cancer detection in solid organ transplant recipients. Explore how biopsy, microscopy, and genetic testing work together in diagnosing junctional epidermolysis bullosa. Icotrokinra demonstrated clinical response rates that were superior to placebo and deucravacitinib. A recent review explored the benefits of biosimilars for patients with moderate to severe chronic plaque psoriasis. A meta-analysis emphasized hidradenitis suppurativa’s early onset and associated diagnostic delays in pediatric patients. AI’s responses about atopic dermatitis improved from 2024 to 2025, but information about skin of color remains limited. Dystrophic EB is more than fragile skin—it can affect the eyes, esophagus, and lead to life-threatening cancers. Researchers revised the Psoriasis Decision Tree, incorporating recent treatment advances that can improve outcomes. Early, appropriate acne therapy can help prevent scarring and emotional distress in young patients. Melanie Anheyer, MD, and colleagues examined the safety and efficacy of herbal treatments for psoriasis. How much do you know about the genetics, pathology, and clinical course of this rare skin fragility disorder? Part 1 reviews patient workup and diagnosis, radiation therapy, and surgery for MCC. For vitiligo, combining phototherapy with topical antioxidants, corticosteroids, or calcineurin inhibitors may be best. An industry-sponsored expert panel issued statements recommending tirbanibulin as first-line actinic keratosis treatment. Emergency department use of diphenhydramine for anaphylaxis and urticaria persists, against AAAAI guidance.