Digital inhalers may help predict the occurrence of acute exacerbations of COPD for patients in an ambulatory setting. Home mold, often attributed to chronic and/or recurring water intrusion, is linked to hypersensitivity pneumonitis. Empagliflozin has kidney protective effects and reduces heart failure in patients with acute myocardial infarction. GLP-1 receptor agonists were linked to lower mortality than DPP4 inhibitors in older patients with cancer and diabetes. Local anesthetic poisoning reports have decreased but reports of lidocaine poisoning and mortality have increased. Remote-scalable cognitive behavioral therapy benefited patients with high-impact chronic pain. Arthroscopically assisted techniques for AC joint reconstruction resulted in persistent benefits up to 15 years. Sequential use of anabolic agents followed by denosumab improved bone mineral density in osteoporotic hip fracture. Survey findings suggest that rates of influenza vaccine uptake declined among US adults from 2020 to 2024. Only 34% of patients with erythema migrans greater than 5 cm are positive for Lyme disease per the CDC’s standard test. Associations between hormone therapy and young-onset breast cancer (diagnosed at younger than 55 years) vary. Patients with higher-severity alopecia areata have a higher prevalence and incidence of comorbid atopic dermatitis. All patients with hypertension should be screened for primary aldosteronism, according to a new clinical practice guideline. A recent survey identified factors driving patients’ decisions to seek acute care for asthma exacerbations. An automated skin prick test was as accurate as traditional tests for detecting birch pollen or dust mite allergy. Rates of diabetic retinal disease have increased in recent years, but its vision-threatening components have decreased. Language preference may impact rates of continuous glucose monitoring prescriptions among patients with type 2 diabetes. A structured research navigator program significantly improved clinical trial enrollment. Spinal oncology trials continue to have substantial racial, ethnic, and geographic disparities in enrollment. A new framework may offer a more sensitive measure of obesity than traditional body mass index.