Halloween fun can turn risky—educate patients and prepare teams to prevent candy, costume, and safety hazards. The AGA issued guidance on evaluating and treating GI complaints for patients with hEDS or HSDs with MCAS and/or POTS.  Blueberry consumption during infancy may improve allergy-related symptom resolution. A new ACCP guideline offers recommendations for selecting biologic agents for adults with severe asthma. High pollen levels correlate with a measurable increase in suicide rates across the US. Inhaled molgramostim significantly improved lung gas exchange and QOL among patients with autoimmune PAP. The declining health of US children is evident in rising rates of chronic disease, obesity, mental illness, and mortality. Training tools dramatically increased pediatricians’ adherence to national guidelines on early peanut introduction. The following is a summary of “Patient and physician perspectives on disease burden in chronic spontaneous urticaria,”… Allergic conjunctivitis insights are transforming clinical understanding and opening pathways to individualized treatment. A recent review highlights sepsis-induced immunosuppression as a key driver of mortality. A ratio-based formula formula for diagnosing pediatric anaphylaxis in the ED performed better than the CCF. Put your expertise to the test—explore T-cell roles, regulatory mechanisms, and cutting-edge detection in food allergies. Researchers in JACI: In Practice offered strategies for diagnosing and eliminating chronic urticaria triggers.  Standard-dose omalizumab and remibrutinib emerged as the most effective options with generally favorable safety. Many patients admitted with angioedema who are stable after the first few hours can be safely managed outside the ICU. Incorporating ALC into the SOFA score improves prognostic accuracy for patients with sepsis. A molecular allergy chip reliably detected allergic asthma, revealing that 73% of the asthma cohort had allergic asthma. Emergency department use of diphenhydramine for anaphylaxis and urticaria persists, against AAAAI guidance. Asthma symptom severity and immune response gender disparities are tied to sex-specific gene expression in immune cells.