AKI impacts short- and long-term outcomes in critically ill patients, making prevention of kidney injury critical. Regional citrate anticoagulation in pediatric renal replacement prolonged circuit survival and reduced clotting and bleeding. A novel humanized anti-citrullinated histone H3 protein monoclonal antibody stopped sepsis progression. A Critical Emergency Medicine Unit significantly reduced mortality among critically ill patients in the emergency department. Arthur Cukiert, MD, PhD, and Christian Dorfer, MD, discuss epilepsy surgery curriculum that goes from diagnosis to post-op. Use of an IDo2 index-informed CDSS significantly decreased duration of vasoactive infusions post-pediatric cardiac surgery. The EzPAP PEP device was as effective as NIV for managing acute exacerbations of COPD in the emergency department. mNGS detected pathogens in PDAP faster and with greater accuracy than conventional dialysis effluent culture testing. Angiotensin II, when added to conventional vasopressor therapy, was tied to a lower mortality risk for patients with shock. Nearly 50% of children and young adults with intracranial gunshot wound injuries who underwent vascular imaging showed PCVI. Research shows that system-level performance interventions are linked to improved survival for patients with cardiac arrest. Hospitalizations and ED visits are often unnecessary among severely impaired or terminally ill nursing home residents. For patients in the ED with acute dyspnea, increased calprotectin was associated with 90-day mortality. A computer-aided tongue-imaging diagnostic system identified severe Mycoplasma pneumoniae pneumonia in hospitalized children. The discovery of a ligand peptide that could serve as a targeted molecular imaging agent for human tissue injury may ... Low-dose melatonin improved drug absorption but did not reduce delirium in individuals with critical illness and who were… Valve surgery offered survival benefits in Candida endocarditis but came with increased hospital stay and cost… Invasive fungal infections were found to be a widespread challenge in ICUs, with prevalence and influence varying by ... High-specificity markers help clarify neurologic prognosis in unconscious individuals after cardiac arrest. ... High intramuscular fat, older age, and low serum albumin can predict mortality in patients starting dialysis, while albumin ...