The ACR presented 28 graded recommendations and 13 ungraded, consensus-based good practice statements.  Dr. Alex McDonald sits down with pediatric oncologist Dr. Neha Vaghasia to explore the landscape of oncology clinical trials. Dr. Rachel Franklin discusses patient trust, humility, and balancing functional care with evidence-based medicine. All T2-biologics improved asthma and nasal outcomes, but anti-IL-4R therapy offered the greatest relief for nasal polyps. A phase 3 trial shows that a biologic therapy significantly reduces nasal polyps and symptoms in chronic rhinosinusitis. Prenatal cfDNA screening combined with fetal DNA enrichment can reliably achieve sufficient fetal fraction for analysis.  Racial and insurance inequities persist in access to medications for opioid use disorder in the US, according to research. Researchers found that COPD prevalence is continuing to increase worldwide even though it is highly preventable. Researchers found that eligibility criteria for KRAS G12C inhibitor trials in NSCLC exclude most real-world patients.  Limitations in the BMI formula, coupled with gender and race biases, can lead to disparities in obesity diagnosis.  Assessing ocular manifestations among patients with COPD may also serve as noninvasive assessment for cardiovascular disease. During COVID-19, pregnant patients who were Black with obesity had higher prepregnancy risks.  Alex McDonald, MD, and Rachel Franklin, MD highlight the importance of whole-person care and prevention. Study highlights key differences between aging-related airway changes and COPD pathology.  A structured research navigator program significantly improved clinical trial enrollment. Spinal oncology trials continue to have substantial racial, ethnic, and geographic disparities in enrollment. Physician's Weekly provides a roundup of phase 3 clinical trials in non-small cell lung cancer that are currently recruiting. IPV screening for women of reproductive age provides a moderate net benefit when followed by multicomponent interventions.  Pavlos Msaouel, MD, PhD, MD Anderson, shares his thoughts on oncology clinical trial with us as well as his personal ... This slideshow reviews research that highlights key endotype differences, immune gene drivers, and gaps in current care.