RFK Jr., as HHS secretary, is seeking changes to vaccine policy, reshaping oversight, funding, and public health strategy. Survey findings suggest that rates of influenza vaccine uptake declined among US adults from 2020 to 2024. Only 34% of patients with erythema migrans greater than 5 cm are positive for Lyme disease per the CDC’s standard test. A novel humanized anti-citrullinated histone H3 protein monoclonal antibody stopped sepsis progression. Postponing thoracoscopic lung surgery following COVID-19 infection resulted in fewer postoperative pulmonary complications. Improving PrEP use in heterosexual minority men requires strategies that integrate HIV risk education and health literacy. Experts shared their techniques for preventing, diagnosing, and treating infections after shoulder arthroplasty. AAP provided updated recommendations for vaccines that differ from those of the current CDC guidelines. A single-page recruitment letter was significantly more likely to result in the recipient’s enrollment in a clinical trial. A rare case of rotavirus-associated myositis involved gastroenteritis and high creatinine kinase with no muscle pain. More than half of transgender women prefer long-acting injectable PrEP, but nearly just as many - 42% - still favor pills. Implementing vaccination programs in EDs could more than triple up-to-date immunization rates among underserved populations. Doxy-PEP was well tolerated, highly acceptable, and highly efficacious for reducing bacterial STI incidence in a recent rando An RSV outbreak in a memory care unit was contained with a multifaceted strategy of limiting visitors and group activities. Among men who have sex with men, PrEP use is driven more by self-esteem and identity than risk. Interventions to enhance mucociliary activity may prevent infections of the nasal sinuses in patients with psoriasis. Research highlights in RSV include data on vaccine efficacy and factors associated with disease severity. Adding human papillomavirus (HPV) testing to urine cytology may improve the detection of bladder cancer. Recent HIV pre-exposure prophylaxis research examines gains in uptake among young adults and barriers to telehealth for PrEP. Recent HIV research highlights the financial cost of mental healthcare and the benefits of early anal cancer screening.