New evidence suggests metformin could enhance muscle strength and mass while reducing mortality in older patients with T2DM. Associations between hormone therapy and young-onset breast cancer (diagnosed at younger than 55 years) vary. A study in JAMA Network Open suggests long-term obesity may trigger aging-related molecular signals in young adults. As pharmacy closures worsen gaps in care, Dr. Eugene Wright, Jr. calls for a reimagining of diabetes management. A pediatric endocrinologist outlines how clinicians can diagnose and treat growth hormone deficiency earlier in children. Even subclinical depression influenced rates of patient retention in a digital weight loss program. Patients who could see that they were earning points for supporting each other lost more weight than a comparison group. Proprioceptive deficits and postural instability were significantly greater in patients with type 2 diabetes. Higher serum levels of LA and n-6 PUFAs were tied to lower risk factors for CV events and T2D. An AI-assisted diagnostic system can accurately estimate bone mineral density and classify osteoporosis category. As rates of MASLD rise, new therapies have emerged, but better diagnostic and monitoring strategies are needed. Expert consensus supports the broader use of continuous glucose monitoring to optimize glycemic control in type 2 diabetes. New findings suggest that thyroid function screening may be warranted in patients with metabolic syndrome. More than half of patients with growth hormone deficiency experience otorhinolaryngological symptoms. Highlights in OB/GYN care examine depression in premature ovarian insufficiency, plus preexisting diabetes in pregnancy. Estrogen increases the levels of the protein annexin-A1 in female mice, suggesting a protective effect against hypertension. While overall diabetes prevalence remained stable from 2013 to 2023, glycemic control worsened in young adults. Skin rash from diabetes medical devices is common, under-recognized, and expected to increase as device use increases. Obesity did not increase surgical risks in thyroidectomy, despite longer operative times.
Researchers conducted a… Better health, not just fewer pounds—weight loss quality is the new priority in modern obesity management.